众盈彩票注册

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环形RNA家族,藏着治疗红斑狼疮新靶点

发表时间:2019-05-15

JINRI,ZHONGGUOKEXUEYUANSHENGWUHUAXUEYUXIBAOSHENGWUXUEYANJIUSUO(YIXIAJIANCHENGZHONGKEYUANSHENGHUASUO)CHENLINGLINGYANJIUZUDEYIXIANGZUIXINFAXIANSHOUDAOMIANYIXITONGJIBINGLINGYUYIXUEJIERENSHIDEGUANZHU。ZHEIXIANGYANJIURANGJISHINIANLAIWUYAOKEZHIDEXITONGXINGHONGBANLANGCHUANG,XIANLUCHULEBEIGONGKEDESHUGUANG。


众盈彩票注册 KEJIRIBAOJIZHECONGZHONGKEYUANSHENGHUASUOLEJIEDAO,GAIYANJIUSHOUCIFAXIANYONGYOUDUTEJIEGOUDEHUANXINGRNAKEYIYIZHITIANRANMIANYIYINZIPKRDEHUOXING。XIBAOSHOUBINGDUGANRANSHI,HUANXINGRNABEIDAGUIMO“QINGCHU”,PKRDEDAOSHIFANGBINGCANYUDAOKANGBINGDUMIANYI,YOUCIZHENGMING,BINGRENTINEIHUANXINGRNADE“DIHANLIANG”YUZISHENMIANYIXINGJIBING——XITONGXINGHONGBANLANGCHUANGMIQIEXIANGGUAN。GAIYANJIUWEIZISHENMIANYIBINGDELINCHUANGZHENDUANHEZHILIAOTIGONGLEXINSILU,XIANGGUANLUNWENFABIAOYUGUOJIQUANWEIXUESHUQIKAN《XIBAO》SHANG。


参与天然免疫系统调控的神秘家族


众盈彩票注册 HUANXINGRNAZUIXINGONGNENG——CANYUTIANRANMIANYIXITONGDIAOKONG,SHIZHEIYIJICHUYANJIUFAXIANDEHEXINTUPODIAN。JINNIANLAI,SUIZHEKEXUEJISHUDEFAZHAN,YINSHENYUXIBAOZHONGSHUYIWANJIDEHUANXINGRNAZHUJIANFUCHUSHUIMIAN。DANYUYIJINGBEIKEXUEJIAFANFUSHENDUPOUXILUNZHENGYURENLEISHENGMINGHUODONGMIQIEXIANGGUANDEXIANXINGRNAXIANGBI,RNAFENZIJIAZUDE“XINREN”——HUANXINGRNASHENSHANGZHIJINRENGYOUXUDUOWEIJIEZHIMI。


CHENLINGLINGYANJIUZUSHIWOGUOHUANXINGRNAQIANYANYANJIULINGYUDEQIAOCHU。JINGGUOZHANGQIYANJIU,TAMENZHUJIANTANXUNDAOZHEIYISHENMIJIAZUDETEXING。CHENLINGLINGJIANGHUANXINGRNADIAOKONGTIANRANMIANYIFANYINGDEGUOCHENGZONGJIEWEI“SHENGDEQUZHE”“SIDEQISUO”“FENGXIANDEYISHENG”。“HUANXINGRNAHUANMANSHENGCHENG、KUAISUJIANGJIE、TESHUERJIJIEGOUSHIQICHENGWEIYILEIDIAOKONGXIBAOTIANRANMIANYIWENTAIDEXINRNAJIAZU。”CHENLINGLINGBIAOSHI。QISHIZAOZAI2017NIAN,GAIKETIZUJIUFAXIANHUANXINGRNAYURENTITIANRANMIANYIXITONGYOUGUAN,QIZAIXIBAOCANYUTIANRANMIANYIYINGDASHISHOUXIAN。


揭示免疫系统调控的“黑匣子”


RENTIPANGDADEMIANYIXITONGDEDIAOKONGGUOCHENGYIZHISHIYIGEHEIXIAZI。ZHIYOUFAXIANLERENTIMIANYIXITONGDIAOKONGDEGUOCHENG,CAINENGZAICIJICHUSHANGYANJIUZHILIAOJIBINGDEFANGFA。ZHONGKEYUANSHENGHUASUOSUOZHANGLIUXIAOLONGDIANPINGGAIYANJIUCHENGGUOSHIRENWEI,CHENLINGLINGYANJIUZUDEZHEICIYANJIUCHENGGUOSHIFAXIANMIANYIXITONGJINGZHUNDIAOKONGFEICHANGZHONGYAODEYIHUAN。


YANJIUZUZAIQIANQIYANJIUZHONGYIJINGZHENGMINGHUANXINGRNASHENGCHENGSUDUHUANMAN。TAMENZAIJINQIYANJIUHUANXINGRNADEERJIJIEGOUGUOCHENGZHONGYOUFAXIAN,ZHEIXIEYONGYOUBIHUANJIEGOUDEHUANXINGRNANEIBUBINGBUJIANDAN,ERSHINENGXINGCHENG16DAO26GEJIANJIDUIJINGHUANJIEGOU。TAMENDUTEDE“ZAOXING”NENGGOUBEITIANRANMIANYIYINZIPKRSHIBIEBINGJIEHE,YOUCI,PKRHUOXINGSHOUDAOYIZHI,KEYIBIMIANTINEIYINPKRGUODUJIHUOYINQIDEMIANYIFANYING。


ERXIBAOZHONGDEHETANGHESUANMEIRNase LZEKEYIRANGPKRHUIFUZIYOUSHEN。ZHEIYILEIMEIZAIXIBAOSHOUBINGDUCIJIXIAKEYIZUOYONGYUHUANXINGRNA,JIANGQI“QIEGE”JIANGJIE,ERHUANMANDEHUANXINGRNASHENGCHENGSUDUBUZUYIHUIBUZHEIXIEBEIJIANGJIEDEHUANXINGRNA,PKRDEYISHIFANGCANYUXIBAODEKANGBINGDUMIANYIGUOCHENG。


遏制红斑狼疮免疫因子过度活跃


众盈彩票注册 “HUANXINGRNAJIUXIANGTAOZAITIANRANMIANYIXITONGZHEIPI‘YEMA’SHANGDE‘JIANGSHENG’。”SHANGHAIJIAOTONGDAXUEYIXUEYUANFUSHURENJIYIYUANSHANGHAIFENGSHIBINGXUEYANJIUSUOSUOZHANGSHENNANJIAOSHOUDALEYIGEBIFANG:KANGGANRANMIANYIXITONGZAIRENTINEIJIUXIANGDANGYUYIPIMA,XUYAOYIGENJIANGSHENGTAOZAISHANGMIAN,SHIQIZAIZHENGQUEDEGUIDAOHEFANGXIANGSHANGBENCHI。“RUGUOKONGZHIDEHAO,JIUNENGBANGZHUJITIDIKANGBINGYUANTIDERUQIN,RUGUOBIANCHENGYIPITUOLEJIANGSHENGDEMA,ZAITINEIHENGCHONGZHIZHUANG,JIUHUIDUIJITIZAOCHENGSUNSHANG。”


众盈彩票注册 LIYONGZHEIXIANGZUIXINFAXIAN,TAYUCHENLINGLINGYANJIUZUHEZUO,CAIJIDAOHONGBANLANGCHUANGBINGRENSHENSHANGDEXUEYEYANGBENBINGJINXINGLEBUFENSHIYAN,DECHULELINGRENXINXIDEJIEGUO。TAMENSHIYONGJISHUSHOUDUANRANGHUANXINGRNAZAIBINGRENLAIYUANDEMIANYIXIBAONEISHULIANGKUOZENG,SUIHOUFAXIAN,BINGRENXIBAONEIGUODUJIHUO“YUNZHUAN”DETIANRANMIANYIYINZIPKRJIQIXIAYOUMIANYIXINHAOTONGLUBEIXIANZHU“KONGZHI”。“ZHEIYIFAXIANKENENGWEIJIANGLAIZUDUANHONGBANLANGCHUANGDEHEXINFABINGTONGLUTIGONGFEICHANGZHONGYAODEZHILIAOBADIAN。”SHENNANSHUO。


众盈彩票注册 ZHEIXIEFAXIANBUJINSHOUCIJIESHILEHUANXINGRNADEJIANGJIETUJINGJIQITESHUERJIJIEGOUTEZHENG,BINGTISHIHUANXINGRNAZUOWEIZHIQIANBEIHULVEDEYILEIXINRNAFENZIJIAZU,KEYITONGGUOXINGCHENGSHUANGLIANJINGHUANJIEGOUFAHUIMIANYIDIAOKONGDEXINGONGNENG。TAMENDE“HUANMANSHENGCHENG”“KUAISUJIANGJIE”YIJI“XINGCHENGJINGHUANJIEGOU”DETEXING,SHIDETAMENZAIDIAOKONGMIANYIWENTAIGUOCHENGZHONGBANYANZHONGYAOJIAOSE。


来源:科技日报